HitPredict

Interactor 1: TSN15 (O95858)
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Gene: TSPAN15

Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 26686862
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 297
+	Hs
		905510 TSN5_HUMAN (7-266): 9.73e-80: 244: 32.58		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		602225 CD9_HUMAN (11-263): 1.03e-52: 173: 15.33		STX2_HUMAN (1-295): 4.47e-72: 225: 42.57
+	Hs
		602251 CD9_HUMAN (11-263): 1.03e-52: 173: 15.33		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		887828 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		887864 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		STX1A_HUMAN (1-293): 1.9e-70: 221: 43.20
+	Hs
		583863 CD53_HUMAN (16-260): 1.42e-47: 160: 19.92		STX2_HUMAN (1-295): 4.47e-72: 225: 42.57
+	Hs
		276316 UPK1B_HUMAN (14-260): 2.47e-48: 163: 17.49		STX1A_HUMAN (1-293): 1.9e-70: 221: 43.20
+	Hs
		602253 CD9_HUMAN (11-263): 1.03e-52: 173: 15.33		STX3_HUMAN (1-295): 6.64e-57: 186: 38.31
+	Hs
		580342 TSN8_HUMAN (14-259): 9.69e-37: 132: 18.36		STX2_HUMAN (1-295): 4.47e-72: 225: 42.57
+	Dm
		1178286 Q7JZI2_DROME (4-260): 1.55e-54: 178: 20.85		STX4_DROME (35-275): 6.39e-50: 169: 27.80
+	Hs
		178458 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95
+	Hs
		2743 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		A0A0C4DGE4_HUMAN (55-234): 1.52e-46: 157: 45.00