HitPredict

Interactor 1: TSN12 (O95859)
Tetraspanin-12 (Tspan-12) (Tetraspan NET-2) (Transmembrane 4 superfamily member 12)
Gene: TSPAN12

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19587294
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0035633 - maintenance of blood-brain barrier
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 798
+	Hs
		403813 TSN7_HUMAN (1-254): 4.94e-62: 198: 21.71		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403847 TSN5_HUMAN (7-248): 1.91e-60: 195: 19.39		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403744 CD63_HUMAN (1-250): 6.27e-60: 193: 26.19		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403820 CD151_HUMAN (3-253): 5.05e-59: 191: 26.64		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		50293 TSN11_HUMAN (10-253): 2.78e-58: 189: 27.09		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403839 CD81_HUMAN (1-251): 3.61e-56: 183: 23.11		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403784 CD9_HUMAN (1-253): 1.9e-51: 171: 22.53		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		156129 TSN4_HUMAN (4-248): 9.57e-50: 166: 24.49		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		326008 TSN15_HUMAN (10-242): 1.04e-47: 163: 19.12		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		396617 CD151_HUMAN (3-253): 5.05e-59: 191: 26.64		ITB2_HUMAN (23-796): 0: 658: 45.50
+	Hs
		574512 CD81_HUMAN (1-251): 3.61e-56: 183: 23.11		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		556422 CD151_HUMAN (3-253): 5.05e-59: 191: 26.64		ITB4_HUMAN (11-727): 0: 566: 33.65
+	Hs
		905571 TSN5_HUMAN (7-248): 1.91e-60: 195: 19.39		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		602289 CD9_HUMAN (1-253): 1.9e-51: 171: 22.53		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		326243 TSN15_HUMAN (10-242): 1.04e-47: 163: 19.12		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		905569 TSN5_HUMAN (7-248): 1.91e-60: 195: 19.39		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06
+	Hs
		101394 CD81_HUMAN (1-251): 3.61e-56: 183: 23.11		F8VNQ3_HUMAN (597-739): 1.67e-16: 86.7: 18.06
+	Hs
		602286 CD9_HUMAN (1-253): 1.9e-51: 171: 22.53		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06
+	Hs
		326236 TSN15_HUMAN (10-242): 1.04e-47: 163: 19.12		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06