Interactor 1: SNAI1 (O95863)
Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna)
Gene: SNAI1

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.747

The method score is based on:

Property Details
Experiments 26794444, 14673164, 21685935, 25314079, 34026424, 20562920, 23011797
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, deacetylase assay
Interaction Type physical association, direct interaction, association, deacetylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 264
Hs

1 482
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024