HitPredict

Interactor 1: SNAI1 (O95863)
Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna)
Gene: SNAI1

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007219 - Notch signaling pathway
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 264 Hs			1 236
+	Hs
		980539 ZN430_HUMAN (13-263): 8.25e-105: 316: 18.53		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		326497 SNAI1_HUMAN (1-264): 1.39e-81: 247: 100.00		NOTC1_HUMAN (67-233): 4.88e-17: 81.9: 29.94
+	Hs
		565090 ZNF7_HUMAN (3-176): 4.48e-69: 227: 7.81		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980426 ZSCA2_HUMAN (3-154): 1.47e-60: 203: 8.86		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980472 ZN431_HUMAN (119-263): 7.06e-55: 187: 31.76		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		563705 ZKSC1_HUMAN (67-234): 1.16e-49: 173: 27.68		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980462 ZN397_HUMAN (2-99): 2.01e-40: 147: 8.16		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Dm
		247292 Q9W0P9_DROME (146-259): 7.64e-37: 136: 56.14		TENM_DROME (2-124): 1.24e-14: 74.7: 17.71
+	Hs
		977952 ZNF92_HUMAN (3-149): 1.12e-30: 121: 3.89		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980477 ZN480_HUMAN (2-72): 2.12e-22: 97.8: 5.63		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		885465 ZN121_HUMAN (150-230): 3.85e-13: 70.5: 43.37		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980381 ZKSC8_HUMAN (7-47): 6.82e-13: 70.1: 2.44		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		804257 ZNF74_HUMAN (3-47): 2.58e-09: 59.3: 8.89		NOTC1_HUMAN (67-233): 4.88e-17: 81.9: 29.94
+	Hs
		1083647 ZNF74_HUMAN (3-47): 2.58e-09: 59.3: 8.89		JAG2_HUMAN (8-209): 1.76e-16: 80.1: 31.86
+	Hs
		980570 ZN107_HUMAN (138-251): 1.22e-09: 60.5: 32.48		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		67863 ZN724_HUMAN (4-47): 2.69e-09: 59.3: 9.09		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		980566 ZN629_HUMAN (4-100): 7.93e-09: 57.7: 4.17		NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84
+	Hs
		1083645 ZNF74_HUMAN (3-47): 2.58e-09: 59.3: 8.89		NOTC3_HUMAN (12-198): 1.58e-11: 65.5: 29.67