Interactor 1: FADS2 (O95864)
Acyl-CoA 6-desaturase (EC 1.14.19.3) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2)
Gene: FADS2

Interactor 2: FADS3 (Q9Y5Q0)
Fatty acid desaturase 3 (FADS3) (EC 1.14.19.-) (Delta(13) fatty acid desaturase) (Delta(13) desaturase)
Gene: FADS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyt-b5~Cyt-b5
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0006629 - lipid metabolic process
GO:0006636 - unsaturated fatty acid biosynthetic process
GO:0016020 - membrane
GO:0016717 - oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 444
Hs

1 445
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024