HitPredict

Interactor 1: DLGP3 (O95886)
Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3)
Gene: DLGAP3

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031594 - neuromuscular junction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 979 Hs			1 304
+	Hs
		327226 DLGP3_HUMAN (1-979): 0: 1306: 100.00		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		327232 DLGP3_HUMAN (1-979): 0: 1306: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		327225 DLGP3_HUMAN (1-979): 0: 1306: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		802758 DLGP2_HUMAN (1-979): 0: 1097: 45.66		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		145942 DLGP1_HUMAN (1-979): 0: 1091: 38.63		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		581066 DLGP2_HUMAN (1-979): 0: 1097: 45.66		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		4616 A0A1B0GTN4_HUMAN (1-979): 0: 1096: 45.66		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		145937 DLGP1_HUMAN (1-979): 0: 1091: 38.63		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		924914 DLGP2_HUMAN (1-979): 0: 1097: 45.66		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		145943 DLGP1_HUMAN (1-979): 0: 1091: 38.63		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		557812 DLGP2_HUMAN (1-979): 0: 1097: 45.66		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		145955 DLGP1_HUMAN (1-979): 0: 1091: 38.63		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		145936 DLGP1_HUMAN (1-979): 0: 1091: 38.63		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		145950 DLGP1_HUMAN (1-979): 0: 1091: 38.63		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Mm
		1246939 DLGP1_MOUSE (1-979): 0: 1061: 37.35		SH3K1_MOUSE (114-186): 2.23e-10: 63.3: 21.33
+	Hs
		802783 DLGP4_HUMAN (1-979): 0: 897: 35.27		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		924968 DLGP4_HUMAN (1-979): 0: 897: 35.27		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		209192 DLGP4_HUMAN (1-979): 0: 897: 35.27		NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00
+	Hs
		557837 DLGP4_HUMAN (1-979): 0: 897: 35.27		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00