HitPredict

Interactor 1: TRUB2 (O95900)
Pseudouridylate synthase TRUB2, mitochondrial (EC 5.4.99.-) (TruB pseudouridine synthase homolog 2) (tRNA pseudouridine 55 synthase TRUB2) (Psi55 synthase TRUB2) (EC 5.4.99.25)
Gene: TRUB2

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 372
+	Hs
		201648 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87
+	Hs
		161926 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		327356 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		327390 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		327533 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		242334 DKC1_HUMAN (58-299): 5.44e-69: 225: 17.46		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Sc
		376706 CBF5_YEAST (58-299): 2.11e-70: 228: 16.27		PABP_YEAST (4-189): 6.12e-39: 147: 24.47
+	Hs
		242446 DKC1_HUMAN (58-299): 5.44e-69: 225: 17.46		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		242456 DKC1_HUMAN (58-299): 5.44e-69: 225: 17.46		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00