HitPredict

Interactor 1: TRUB2 (O95900)
Pseudouridylate synthase TRUB2, mitochondrial (EC 5.4.99.-) (TruB pseudouridine synthase homolog 2) (tRNA pseudouridine 55 synthase TRUB2) (Psi55 synthase TRUB2) (EC 5.4.99.25)
Gene: TRUB2

Interactor 2: FAKD2 (Q9NYY8)
FAST kinase domain-containing protein 2, mitochondrial
Gene: FASTKD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27667664, 28514442, 32877691, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0035770 - ribonucleoprotein granule GO:0070131 - positive regulation of mitochondrial translation
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 710
+	Hs
		327508 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		FAKD4_HUMAN (159-702): 5.91e-158: 472: 19.12
+	Hs
		327479 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		FAKD5_HUMAN (156-637): 1.64e-114: 364: 16.14
+	Hs
		327454 TRUB2_HUMAN (1-331): 2.26e-142: 407: 100.00		FAKD1_HUMAN (161-519): 2.89e-23: 107: 16.94