Interactor 1: ECD (O95905)
Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1)
Gene: ECD

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 26711270, 28514442, 28561026, 33961781, 35235311, 28515276, 34079125, 35271311
Identification Methods pull down, affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 644
Hs

1 2335
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024