HitPredict

Interactor 1: CBX7 (O95931)
Chromobox protein homolog 7
Gene: CBX7

Interactor 2: PHC3 (Q8NDX5)
Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)
Gene: PHC3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	27705803, 26186194, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031519 - PcG protein complex GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 251 Hs			1 983
+	Hs
		123290 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PHC3_HUMAN (1-983): 3.72e-88: 305: 100.00
+	Hs
		1059177 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		PHC3_HUMAN (1-983): 3.72e-88: 305: 100.00
+	Hs
		327838 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		PHC1_HUMAN (33-983): 9.51e-36: 148: 23.90
+	Hs
		123303 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		SCMH1_HUMAN (552-982): 1.15e-38: 155: 17.83
+	Hs
		327853 CBX7_HUMAN (1-251): 1.05e-81: 247: 100.00		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Hs
		123234 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PHC1_HUMAN (33-983): 9.51e-36: 148: 23.90
+	Hs
		123346 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		SCML2_HUMAN (553-982): 5.47e-34: 141: 17.40
+	Hs
		123342 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		SCML1_HUMAN (799-982): 6.24e-33: 132: 22.28
+	Hs
		1059182 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		SCMH1_HUMAN (552-982): 1.15e-38: 155: 17.83
+	Hs
		943062 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		PHC1_HUMAN (33-983): 9.51e-36: 148: 23.90
+	Hs
		1027335 CBX3_HUMAN (9-157): 2.45e-42: 144: 22.00		SCML2_HUMAN (553-982): 5.47e-34: 141: 17.40
+	Hs
		1059204 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		SCML2_HUMAN (553-982): 5.47e-34: 141: 17.40
+	Dr
		1193375 Q804D1_DANRE (1-175): 1.64e-41: 149: 35.75		PHC2_DANRE (172-983): 1.93e-30: 131: 23.58
+	Hs
		123280 CBX4_HUMAN (1-242): 2.24e-55: 187: 33.60		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Hs
		1059202 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		SCML1_HUMAN (799-982): 6.24e-33: 132: 22.28
+	Hs
		1026998 CBX3_HUMAN (9-157): 2.45e-42: 144: 22.00		MDC1_HUMAN (38-926): 2.52e-24: 112: 9.32
+	Hs
		1056829 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		MDC1_HUMAN (38-926): 2.52e-24: 112: 9.32
+	Hs
		1059170 CBX2_HUMAN (2-216): 1.06e-38: 142: 26.05		PHC2_HUMAN (30-566): 3.66e-17: 88.9: 27.02
+	Mm
		1208472 Q9DCC5_MOUSE (9-157): 2.45e-42: 144: 22.00		ADNP2_MOUSE (285-699): 2.18e-12: 73.5: 21.34
+	Dm
		1369161 Q9W396_DROME (10-156): 1.05e-40: 141: 24.34		SMBT_DROME (899-981): 3.54e-12: 72.7: 34.94