Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: DNMT1 (P26358)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Gene: DNMT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21670149
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006346 - DNA methylation-dependent heterochromatin formation
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 291
Hs

1 1616
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024