HitPredict

Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: ZBT46 (Q86UZ6)
Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)
Gene: ZBTB46

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 589
+	Hs
		311994 MBD3_HUMAN (1-291): 3.13e-166: 464: 100.00		ZBT7A_HUMAN (10-561): 6.19e-99: 314: 19.46
+	Mm
		1145328 MBD3_MOUSE (1-267): 3.1e-165: 461: 97.75		ZBT7B_MOUSE (10-492): 4.29e-78: 258: 19.72
+	Hs
		328557 MBD3_HUMAN (1-291): 3.13e-166: 464: 100.00		HIC1_HUMAN (6-492): 1.93e-73: 250: 17.71
+	Hs
		328534 MBD3_HUMAN (1-291): 3.13e-166: 464: 100.00		ZBT16_HUMAN (93-564): 5.21e-56: 202: 13.99
+	Hs
		328501 MBD3_HUMAN (1-291): 3.13e-166: 464: 100.00		BCL6_HUMAN (131-504): 3.13e-47: 178: 16.62
+	Hs
		51223 MBD3_HUMAN (1-291): 3.13e-166: 464: 100.00		ZBT7C_HUMAN (475-560): 3.96e-11: 68: 15.73
+	Hs
		1246258 MB3L2_HUMAN (67-258): 1.65e-63: 200: 30.93		ZBT10_HUMAN (12-580): 2.5e-86: 288: 31.00