Interactor 1: APCL (O95996)
Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like)
Gene: APC2

Interactor 2: AXIN2 (Q9Y2T1)
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Gene: AXIN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 10021369
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Axin_b-cat_bind, RGS~SAMP
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008013 - beta-catenin binding
GO:0030877 - beta-catenin destruction complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 2303
Hs

1 843
+ Mm
+ Mm
+ Hs
+ Hs
+ Rn
+ Xl
+ Dm
+ Dm
+ Ce
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024