Interactor 1: PTTG1 (O95997)
Securin (Esp1-associated protein) (Pituitary tumor-transforming gene 1 protein) (Tumor-transforming protein 1) (hPTTG)
Gene: PTTG1
Interactor 2: ESPL1 (Q14674)
Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)
Gene: ESPL1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.90 | 0.925 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 26496610, 28514442, 33961781, 17604273, 20360068, 19117984, 25750436, 24781523 |
| Identification Methods | affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Peptidase_C50~Securin |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045143 - homologous chromosome segregation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
