Interactor 1: PTTG1 (O95997)
Securin (Esp1-associated protein) (Pituitary tumor-transforming gene 1 protein) (Tumor-transforming protein 1) (hPTTG)
Gene: PTTG1

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.767

The method score is based on:

Property Details
Experiments 16479161, 35440621, 10922056, 20080579, 12956947, 25490258, 25825779, 21700221, 27114510, 27259151, 29973362, 29549242, 32393902, 16413484, 18722180, 34942047, 35634770, 11562349, 18485873, 23091007 and 3 others

more...

Identification Methods affinity chromatography technology, pull down, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006281 - DNA repair
GO:0051301 - cell division
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 202
Hs

1 496
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024