Interactor 1: BCL10 (O95999)
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)
Gene: BCL10

Interactor 2: CAR11 (Q9BXL7)
Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)
Gene: CARD11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 24074955, 22528498, 11278692, 18806265, 25548215, 21157432, 27777308, 19118383, 30279415, 35099607, 19815501, 19444310, 21513986, 18625728, 23690623, 12154360, 17948050
Identification Methods x-ray crystallography, pull down, affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD
Common GO terms GO:0001772 - immunological synapse
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction
GO:0032449 - CBM complex
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 233
Hs

1 1154
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024