Interactor 1: PAK4 (O96013)
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)
Gene: PAK4

Interactor 2: PAK6 (Q9NQU5)
Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)
Gene: PAK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 32707033
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~PBD, PBD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 591
Hs

1 681
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ At
+ At
+ Dm
+ At
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Ce
+ Sc
+ Sp

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Last updated: 15 Jul 2024