Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Interactor 2: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.96 | 1.00 | 0.982 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25361978, 23178491, 18948271, 11901158, 12024051, 12909615, 12676583, 11438675, 16794575, 18239682 |
Identification Methods | enzymatic study, biochemical, unspecified method, affinity chromatography technology, pull down, x-ray crystallography, cross-linking study, protein kinase assay |
Interaction Type | direct interaction, association, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | FHA~FHA, FHA~Pkinase, Pkinase~Pkinase |
Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0000086 - G2/M transition of mitotic cell cycle GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus and 31 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024