Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Interactor 2: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 25361978, 23178491, 18948271, 11901158, 12024051, 12909615, 12676583, 11438675, 16794575, 18239682
Identification Methods enzymatic study, biochemical, unspecified method, affinity chromatography technology, pull down, x-ray crystallography, cross-linking study, protein kinase assay
Interaction Type direct interaction, association, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains FHA~FHA, FHA~Pkinase, Pkinase~Pkinase
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 31 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 543
Hs

1 543
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+ At
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Last updated: 15 Jul 2024