Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Interactor 2: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 15647386, 12447371
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006302 - double-strand break repair
GO:0031573 - mitotic intra-S DNA damage checkpoint signaling
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 543
Hs

1 934
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024