HitPredict

Interactor 1: ACL6A (O96019)
Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)
Gene: ACTL6A

Interactor 2: HDGR2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)
Gene: HDGFL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0006310 - DNA recombination GO:0006338 - chromatin remodeling GO:1905168 - positive regulation of double-strand break repair via homologous recombination
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 429 Hs			1 671
+	Hs
		932229 ACTC_HUMAN (5-428): 0: 547: 34.67		HDGR2_HUMAN (1-671): 9.52e-82: 274: 100.00
+	Hs
		855450 ACTC_HUMAN (5-428): 0: 547: 34.67		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		331475 ACL6A_HUMAN (1-429): 0: 597: 100.00		HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78
+	Ce
		483546 ACT3_CAEEL (9-428): 0: 551: 35.00		Q18033_CAEEL (192-461): 2.12e-12: 72.8: 18.41
+	Dm
		54871 ACT6_DROME (9-428): 0: 546: 34.29		A1ZA72_DROME (72-671): 6.39e-10: 65.1: 14.60