HitPredict

Interactor 1: ACL6A (O96019)
Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)
Gene: ACTL6A

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 29028833, 33961781, 28561026, 35271311, 17643375, 17721549, 16230350
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~TIP49
Common GO terms GO:0000723 - telomere maintenance
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006275 - regulation of DNA replication
and 19 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 429
Hs

1 463
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Last updated: 15 Jul 2024