HitPredict

Interactor 1: CCNE2 (O96020)
G1/S-specific cyclin-E2
Gene: CCNE2

Interactor 2: CKS1 (P61024)
Cyclin-dependent kinases regulatory subunit 1 (CKS-1)
Gene: CKS1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0019901 - protein kinase binding GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 404 Hs			1 79
+	Hs
		624570 CCNE1_HUMAN (1-402): 3.2e-126: 372: 47.16		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	Hs
		624551 CCNE1_HUMAN (1-402): 3.2e-126: 372: 47.16		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	Hs
		303840 CCNB2_HUMAN (3-359): 1.26e-102: 311: 21.74		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	Hs
		538505 CCNB1_HUMAN (2-362): 3.28e-102: 311: 20.92		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	Hs
		303832 CCNB2_HUMAN (3-359): 1.26e-102: 311: 21.74		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	Hs
		538483 CCNB1_HUMAN (2-362): 3.28e-102: 311: 20.92		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	At
		188178 CCB24_ARATH (12-367): 1.11e-99: 305: 17.94		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		1352139 CCB24_ARATH (12-367): 1.11e-99: 305: 17.94		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	At
		188149 CCB12_ARATH (11-370): 6.32e-99: 303: 21.47		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		1106919 CCB12_ARATH (11-370): 6.32e-99: 303: 21.47		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	At
		188148 CCA23_ARATH (1-362): 1.76e-95: 294: 20.31		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		188167 CCB23_ARATH (6-358): 1.54e-95: 294: 18.56		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	Hs
		895411 CCNA1_HUMAN (16-367): 2.97e-93: 289: 20.11		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	At
		1324477 CCA31_ARATH (27-366): 1.96e-95: 291: 23.71		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	Hs
		706795 CCNA1_HUMAN (16-367): 2.97e-93: 289: 20.11		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	At
		48925 CCA33_ARATH (50-366): 3.04e-93: 284: 22.19		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		48953 CCA33_ARATH (50-366): 3.04e-93: 284: 22.19		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	At
		188151 CCA34_ARATH (19-366): 6.96e-91: 280: 21.43		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	Hs
		590135 CCNA2_HUMAN (2-366): 3.54e-90: 280: 18.73		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	At
		1108315 CCA34_ARATH (19-366): 6.96e-91: 280: 21.43		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57