HitPredict

Interactor 1: O96660 (O96660)
Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member)
Gene: Smox

Interactor 2: EGON (P15370)
Protein embryonic gonad (Nuclear receptor subfamily 0 group A member 3) (Protein eagle) (Protein spready)
Gene: eg

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0030154 - cell differentiation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 486 Dm			1 373
+	Hs
		369398 SMAD3_HUMAN (1-486): 0: 535: 57.61		ESR1_HUMAN (3-161): 7.73e-56: 194: 32.35
+	Hs
		171391 SMAD9_HUMAN (1-486): 0: 553: 51.02		PPARD_HUMAN (1-147): 1.52e-48: 171: 29.73
+	Hs
		377251 SMAD3_HUMAN (1-486): 0: 535: 57.61		GCR_HUMAN (2-191): 1.11e-49: 180: 26.43
+	Hs
		369685 SMAD2_HUMAN (1-486): 1.58e-180: 515: 53.71		ESR1_HUMAN (3-161): 7.73e-56: 194: 32.35
+	Hs
		740500 SMAD3_HUMAN (1-486): 0: 535: 57.61		PPARG_HUMAN (1-149): 9.63e-49: 173: 30.00
+	Hs
		782518 SMAD3_HUMAN (1-486): 0: 535: 57.61		HNF4A_HUMAN (1-138): 5.23e-45: 163: 25.34
+	Hs
		587178 SMAD2_HUMAN (1-486): 1.58e-180: 515: 53.71		RXRA_HUMAN (3-84): 2.14e-44: 161: 37.81
+	Mm
		816999 SMAD3_MOUSE (1-486): 0: 535: 57.61		VDR_MOUSE (3-73): 3.33e-18: 87.4: 53.52
+	Hs
		509931 SMAD3_HUMAN (1-486): 0: 535: 57.61		VDR_HUMAN (3-73): 4.13e-18: 87: 53.52
+	Ce
		954781 DAF8_CAEEL (2-486): 1.93e-153: 449: 29.40		NHR69_CAEEL (1-143): 6.06e-44: 157: 24.48
+	Hs
		782538 SMAD4_HUMAN (8-483): 1.17e-143: 424: 32.66		HNF4A_HUMAN (1-138): 5.23e-45: 163: 25.34