HitPredict

Interactor 1: O97102 (O97102)
Small ubiquitin-related modifier (SUMO)
Gene: Sumo

Interactor 2: Q9XYM5 (Q9XYM5)
LD27861p (Suppressor of variegation 2-10, isoform E) (Zimp-B)
Gene: Su(var)2-10

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	31901446
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Rad60-SLD~zf-MIZ
Common GO terms	GO:0005634 - nucleus GO:0016925 - protein sumoylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 90 Dm			1 522
+	Hs
		879167 SUMO3_HUMAN (1-90): 5.77e-37: 121: 69.15		PIAS3_HUMAN (1-509): 0: 556: 41.55
+	Hs
		902827 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS3_HUMAN (1-509): 0: 556: 41.55
+	Mm
		222291 SUMO1_MOUSE (7-88): 2.32e-32: 109: 53.66		PIAS3_MOUSE (1-509): 0: 555: 41.63
+	Hs
		278009 SUMO3_HUMAN (1-90): 5.77e-37: 121: 69.15		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Hs
		278020 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Hs
		278250 SUMO3_HUMAN (1-90): 5.77e-37: 121: 69.15		PIAS2_HUMAN (1-519): 2.38e-180: 522: 39.93
+	Hs
		102146 SUMO5_HUMAN (1-88): 3.68e-33: 111: 47.42		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Rn
		1140374 SUMO3_RAT (1-88): 3.4e-37: 122: 69.57		PIAS2_RAT (1-519): 8.81e-180: 519: 39.74
+	Hs
		278040 SUMO1_HUMAN (7-88): 2.32e-32: 109: 53.66		PIAS1_HUMAN (1-510): 0: 531: 41.52
+	Hs
		278253 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS2_HUMAN (1-519): 2.38e-180: 522: 39.93
+	Hs
		102147 SUMO5_HUMAN (1-88): 3.68e-33: 111: 47.42		PIAS2_HUMAN (1-519): 2.38e-180: 522: 39.93
+	Hs
		278256 SUMO1_HUMAN (7-88): 2.32e-32: 109: 53.66		PIAS2_HUMAN (1-519): 2.38e-180: 522: 39.93
+	Hs
		879136 SUMO3_HUMAN (1-90): 5.77e-37: 121: 69.15		PIAS4_HUMAN (1-423): 7.01e-174: 501: 43.06
+	Hs
		902668 SUMO2_HUMAN (1-89): 1.32e-35: 117: 67.02		PIAS4_HUMAN (1-423): 7.01e-174: 501: 43.06
+	Rn
		78200 SUMO3_RAT (1-88): 3.4e-37: 122: 69.57		B5DFF9_RAT (1-424): 4.5e-171: 494: 42.49
+	Ce
		879077 SUMO_CAEEL (1-88): 4.82e-33: 111: 47.78		GEI17_CAEEL (129-518): 4.83e-92: 299: 30.65
+	At
		1147334 SUMO2_ARATH (3-89): 1.46e-37: 123: 49.43		SIZ1_ARATH (5-518): 5.54e-67: 234: 19.66
+	At
		878961 SUMO1_ARATH (3-86): 1.06e-34: 115: 50.00		SIZ1_ARATH (5-518): 5.54e-67: 234: 19.66
+	At
		1147333 SUMO3_ARATH (3-88): 1.56e-32: 110: 43.18		SIZ1_ARATH (5-518): 5.54e-67: 234: 19.66
+	Rn
		89025 SUMO3_RAT (1-88): 3.4e-37: 122: 69.57		D4AE97_RAT (59-435): 2.7e-58: 210: 21.28