HitPredict

Interactor 1: PLK4 (O97143)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK)
Gene: SAK

Interactor 2: RS27A (P15357)
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RpS27A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	19171756, 24184097
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 769 Dm			1 156
+	Dm
		332721 PLK4_DROME (1-769): 0: 711: 100.00		Q9W418_DROME (1-78): 2.76e-41: 145: 97.44
+	At
		1091642 CDPKB_ARATH (6-427): 6.04e-152: 454: 23.02		UBQ3_ARATH (1-77): 8.32e-36: 127: 94.81
+	At
		1091676 CDPK3_ARATH (5-438): 2.36e-147: 443: 23.30		UBQ3_ARATH (1-77): 8.32e-36: 127: 94.81
+	At
		1092417 CDPKQ_ARATH (5-449): 9.97e-147: 440: 23.18		UBQ3_ARATH (1-77): 8.32e-36: 127: 94.81
+	At
		1091633 CDPK5_ARATH (5-449): 3.29e-144: 436: 23.84		UBQ3_ARATH (1-77): 8.32e-36: 127: 94.81
+	At
		1091641 KIN10_ARATH (3-283): 5.13e-134: 408: 33.69		UBQ3_ARATH (1-77): 8.32e-36: 127: 94.81
+	At
		955189 KIN11_ARATH (2-268): 8.7e-131: 400: 33.96		UBQ3_ARATH (1-77): 8.32e-36: 127: 94.81
+	Hs
		160345 AURKA_HUMAN (11-267): 2.54e-54: 194: 38.91		UBB_HUMAN (1-76): 7.7e-35: 122: 100.00
+	Hs
		475136 AURKB_HUMAN (10-267): 4.08e-54: 192: 39.92		UBB_HUMAN (1-76): 7.7e-35: 122: 100.00