Interactor 1: ADH1 (P00330)
Alcohol dehydrogenase 1 (EC 1.1.1.1) (EC 1.1.1.54) (EC 1.1.1.78) (Alcohol dehydrogenase I) (ADHI) (NADH-dependent methylglyoxal reductase) (YADH-1)
Gene: ADH1

Interactor 2: ADH1 (P00330)
Alcohol dehydrogenase 1 (EC 1.1.1.1) (EC 1.1.1.54) (EC 1.1.1.78) (Alcohol dehydrogenase I) (ADHI) (NADH-dependent methylglyoxal reductase) (YADH-1)
Gene: ADH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 25157460, 26743849, 29557065, 19343713, 23850452
Identification Methods x-ray crystallography, affinity chromatography technology, biochemical, ion mobility mass spectrometry of complexes, blue native page
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ADH_N~ADH_N, ADH_N~ADH_zinc_N, ADH_zinc_N~ADH_zinc_N
Common GO terms GO:0000947 - amino acid catabolic process to alcohol via Ehrlich pathway
GO:0004022 - alcohol dehydrogenase (NAD+) activity
GO:0004552 - octanol dehydrogenase (NAD+) activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 7 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 348
Sc

1 348
+ Sc
+ Sc
+ Ce
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Sp
+ Ph
+ Hs
+ Hs
+ Sc
+ Ec
+ Hp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024