Interactor 1: DHE3 (P00367)
Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)
Gene: GLUD1

Interactor 2: SIR4 (Q9Y6E7)
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 2.3.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein biotinylase sirtuin-4) (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4)
Gene: SIRT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 25525879
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006541 - glutamine metabolic process
GO:0070403 - NAD+ binding
GO:0072350 - tricarboxylic acid metabolic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 558
Hs

1 314
+ Mm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024