HitPredict

Interactor 1: NB5R3 (P00387)
NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1)
Gene: CYB5R3

Interactor 2: RTN4 (Q9NQC3)
Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5)
Gene: RTN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 301 Hs			1 1192
+	Hs
		306962 NB5R3_HUMAN (1-301): 4.03e-123: 355: 100.00		RTN3_HUMAN (269-1191): 7.4e-55: 210: 22.06
+	Hs
		335433 NB5R3_HUMAN (1-301): 4.03e-123: 355: 100.00		RTN1_HUMAN (419-1192): 1e-50: 194: 23.36
+	Hs
		258890 NB5R3_HUMAN (1-301): 4.03e-123: 355: 100.00		RTN2_HUMAN (775-1185): 4.86e-44: 171: 25.39