Interactor 1: COX1 (P00395)
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)
Gene: MT-CO1

Interactor 2: COX2 (P00403)
Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II)
Gene: MT-CO2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22252130
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains COX1~COX2, COX1~COX2_TM
Common GO terms GO:0001666 - response to hypoxia
GO:0004129 - cytochrome-c oxidase activity
GO:0005743 - mitochondrial inner membrane
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 513
Hs

1 227
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024