HitPredict

Interactor 1: COX1 (P00395)
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)
Gene: MT-CO1

Interactor 2: COX41 (P13073)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)
Gene: COX4I1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	33961781, 22252130, 23260140
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, blue native page
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	COX1~COX4
Common GO terms	GO:0004129 - cytochrome-c oxidase activity GO:0005743 - mitochondrial inner membrane GO:0005751 - mitochondrial respiratory chain complex IV GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen GO:0031966 - mitochondrial membrane and 1 others more... GO:0045333 - cellular respiration
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 169
+	Hs
		335692 COX1_HUMAN (1-513): 0: 717: 100.00		COX42_HUMAN (1-169): 3.8e-66: 201: 49.71