HitPredict

Interactor 1: COX1 (P00395)
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)
Gene: MT-CO1

Interactor 2: EDNRA (P25101)
Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)
Gene: EDNRA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001666 - response to hypoxia
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 427
+	Hs
		335660 COX1_HUMAN (1-513): 0: 717: 100.00		OPRM_HUMAN (22-423): 2.24e-68: 224: 22.33
+	Hs
		335661 COX1_HUMAN (1-513): 0: 717: 100.00		APJ_HUMAN (71-412): 6.25e-67: 219: 22.03
+	Hs
		335657 COX1_HUMAN (1-513): 0: 717: 100.00		GRPR_HUMAN (100-387): 1.74e-36: 139: 31.96
+	Hs
		198085 COX1_HUMAN (1-513): 0: 717: 100.00		MTLR_HUMAN (84-377): 5.73e-16: 81.3: 22.39