HitPredict

Interactor 1: COX1 (P00401)
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)
Gene: COX1

Interactor 2: COX2 (P00410)
Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II)
Gene: COX2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 24478450, 30224355, 37968396, 22904327, 23434581, 29746825, 28821616, 19858289, 23897805
Identification Methods pull down, biochemical, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains COX1~COX2, COX1~COX2_TM
Common GO terms GO:0004129 - cytochrome-c oxidase activity
GO:0005739 - mitochondrion
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0009060 - aerobic respiration
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 534
Sc

1 251
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024