HitPredict

Interactor 1: COX2 (P00403)
Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II)
Gene: MT-CO2

Interactor 2: COX41 (P13073)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)
Gene: COX4I1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 29568061, 34079125, 33961781
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains COX2~COX4, COX2_TM~COX4
Common GO terms GO:0004129 - cytochrome-c oxidase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 227
Hs

1 169
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024