Interactor 1: RIR1 (P00452)
Ribonucleoside-diphosphate reductase 1 subunit alpha (EC 1.17.4.1) (Protein B1) (Ribonucleoside-diphosphate reductase 1 R1 subunit) (Ribonucleotide reductase 1)
Gene: nrdA
Interactor 2: RIR2 (P69924)
Ribonucleoside-diphosphate reductase 1 subunit beta (EC 1.17.4.1) (Protein B2) (Protein R2) (Ribonucleotide reductase 1)
Gene: nrdB
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.90 | 1.00 | 0.953 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16606699, 9309223, 22160671, 22727814, 17726094, 32217749 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, cosedimentation in solution, x ray scattering, transmission electron microscopy, molecular sieving, pull down, electron microscopy 3D single particle reconstruction |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ATP-cone~Ribonuc_red_sm, Ribonuc_red_lgC~Ribonuc_red_sm |
| Common GO terms | GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0005829 - cytosol GO:0005971 - ribonucleoside-diphosphate reductase complex GO:0009185 - ribonucleoside diphosphate metabolic process GO:0009263 - deoxyribonucleotide biosynthetic process and 2 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
