Interactor 1: HPRT (P00492)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)
Gene: HPRT1

Interactor 2: HPRT (P00492)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)
Gene: HPRT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 25416956, 32296183, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyltran~Pribosyltran
Common GO terms GO:0000166 - nucleotide binding
GO:0000287 - magnesium ion binding
GO:0001913 - T cell mediated cytotoxicity
GO:0001975 - response to amphetamine
GO:0004422 - hypoxanthine phosphoribosyltransferase activity
and 26 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 218
Hs

1 218
+ Mm
+ Hs
+ Hs
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024