Interactor 1: HPRT (P00492)
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)
Gene: HPRT1
Interactor 2: PRDC1 (Q9NRG1)
Phosphoribosyltransferase domain-containing protein 1
Gene: PRTFDC1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.978 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 25416956, 16189514, 25910212, 28514442, 33961781, 34349018, 31515488, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, validated two hybrid, two hybrid array, two hybrid prey pooling approach, two hybrid bait and prey pooling approach, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pribosyltran~Pribosyltran |
| Common GO terms | GO:0000166 - nucleotide binding GO:0000287 - magnesium ion binding GO:0005829 - cytosol GO:0006166 - purine ribonucleoside salvage GO:0032263 - GMP salvage and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
