HitPredict

Interactor 1: KAP0 (P00514)
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]
Gene: PRKAR1A

Interactor 2: KAP0 (P00514)
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]
Gene: PRKAR1A

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 20159461, 24316401, 12860132
Identification Methods molecular sieving, x-ray crystallography, x ray scattering, nuclear magnetic resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, RIIa~RIIa
Common GO terms GO:0001707 - mesoderm formation
GO:0001772 - immunological synapse
GO:0001932 - regulation of protein phosphorylation
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005737 - cytoplasm
and 20 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 380
Bt

1 380
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce
+ Dm
+ Bt
+ Hs
+ Sc
+ Sp
+ Zm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024