Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 16397227, 12654250, 8242749
Identification Methods enzymatic study, unspecified method
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000287 - magnesium ion binding
GO:0000400 - four-way junction DNA binding
GO:0000405 - bubble DNA binding
GO:0001726 - ruffle
and 149 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 1130
+ Mm
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+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Dm
+ Rn
+ Gg
+ Hs
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+ Rn
+ Rn

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Last updated: 15 Jul 2024