Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1
Interactor 2: JAK1 (P23458)
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Gene: JAK1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 9774693 |
Identification Methods | pull down |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
Common GO terms | GO:0004713 - protein tyrosine kinase activity GO:0004715 - non-membrane spanning protein tyrosine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 1 others more... |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024