HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: CXA8 (P48165)
Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70)
Gene: GJA8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 433
+	Rn
		435433 SRC_RAT (13-510): 0: 549: 38.11		CXA1_RAT (1-343): 9.46e-123: 363: 39.77
+	Hs
		522752 SRC_HUMAN (13-510): 0: 547: 38.58		CXA1_HUMAN (1-343): 1.53e-122: 362: 39.48
+	Mm
		403416 SRC_MOUSE (13-510): 0: 545: 38.19		CXA1_MOUSE (1-343): 9.46e-123: 363: 39.77
+	Hs
		433245 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		CXA1_HUMAN (1-343): 1.53e-122: 362: 39.48
+	Hs
		412232 FYN_HUMAN (18-510): 0: 543: 38.64		CXB7_HUMAN (4-243): 1.42e-106: 315: 43.80
+	Hs
		433391 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		CXB7_HUMAN (4-243): 1.42e-106: 315: 43.80
+	Rn
		435256 CSK_RAT (61-500): 1.79e-155: 472: 37.72		CXA1_RAT (1-343): 9.46e-123: 363: 39.77
+	Hs
		433835 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		CXB7_HUMAN (4-243): 1.42e-106: 315: 43.80
+	Hs
		566953 CSK_HUMAN (61-500): 1.81e-155: 472: 37.72		CXA1_HUMAN (1-343): 1.53e-122: 362: 39.48
+	Hs
		433414 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		CXD3_HUMAN (1-238): 1.26e-95: 290: 40.34
+	Hs
		433886 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		CXD3_HUMAN (1-238): 1.26e-95: 290: 40.34