HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: PAXI (P49023)
Paxillin
Gene: PXN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 36736316, 25795725
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0034446 - substrate adhesion-dependent cell spreading
GO:0038191 - neuropilin binding
GO:0043542 - endothelial cell migration
GO:0051496 - positive regulation of stress fiber assembly
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1130
Hs

1 591
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024