Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: STA5B (P51692)
Signal transducer and activator of transcription 5B
Gene: STAT5B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.735

The method score is based on:

Property Details
Experiments 31175292
Identification Methods surface plasmon resonance, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, SH2~SH2, SH2~SH3_1
Common GO terms GO:0000278 - mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 787
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Last updated: 15 Jul 2024