Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: 3BP2 (P78314)
SH3 domain-binding protein 2 (3BP-2)
Gene: SH3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments unassigned3713
Identification Methods fluorescence polarization spectroscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, SH2~SH2, PH~SH3_1, SH2~SH3_1
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0017124 - SH3 domain binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 561
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024