Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: PKD1 (P98161)
Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein)
Gene: PKD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17474147
Identification Methods peptide array
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007204 - positive regulation of cytosolic calcium ion concentration
GO:0030155 - regulation of cell adhesion
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 4303
+ Hs
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Last updated: 15 Jul 2024