HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11431473
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0017124 - SH3 domain binding GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 881
+	Hs
		337603 ABL1_HUMAN (1-1130): 0: 984: 100.00		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		337453 ABL1_HUMAN (1-1130): 0: 984: 100.00		ABR_HUMAN (1-412): 3.62e-71: 253: 19.17
+	Mm
		337622 ABL1_MOUSE (1-1130): 0: 901: 85.00		3BP1_MOUSE (1-618): 1.8e-83: 284: 38.35
+	Hs
		337325 ABL1_HUMAN (1-1130): 0: 984: 100.00		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Hs
		523026 SRC_HUMAN (13-510): 0: 547: 38.58		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		411763 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		986382 BTK_HUMAN (5-501): 5.05e-156: 481: 36.56		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		523225 SRC_HUMAN (13-510): 0: 547: 38.58		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		442896 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Mm
		763398 FYN_MOUSE (18-510): 0: 542: 38.64		RHG33_MOUSE (210-751): 3.35e-68: 249: 20.50
+	Hs
		411755 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		RHG21_HUMAN (10-685): 1.4e-69: 254: 16.46
+	Hs
		433814 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		RHG21_HUMAN (10-685): 1.4e-69: 254: 16.46
+	Hs
		433879 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		RHG12_HUMAN (53-427): 1.04e-63: 232: 17.90
+	Hs
		522938 SRC_HUMAN (13-510): 0: 547: 38.58		RHG01_HUMAN (250-412): 3.19e-19: 93.6: 32.73
+	Hs
		64648 SRC_HUMAN (13-510): 0: 547: 38.58		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		64642 FYN_HUMAN (18-510): 0: 543: 38.64		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		64641 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		506538 FRK_HUMAN (31-511): 1.18e-176: 529: 39.80		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Hs
		442768 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Hs
		64643 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41