HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: SNX12 (Q9UMY4)
Sorting nexin-12
Gene: SNX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030100 - regulation of endocytosis
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 162
+	Hs
		234882 ABL1_HUMAN (1-1130): 0: 984: 100.00		SNX3_HUMAN (5-162): 2.59e-55: 173: 79.75
+	Ce
		371325 ABL1_CAEEL (3-1130): 0: 606: 32.11		LST4_CAEEL (2-161): 7.02e-31: 118: 22.09
+	Hs
		234894 SRC_HUMAN (13-510): 0: 547: 38.58		SNX3_HUMAN (5-162): 2.59e-55: 173: 79.75
+	Hs
		412408 FYN_HUMAN (18-510): 0: 543: 38.64		SNX12_HUMAN (1-162): 4.7e-56: 174: 100.00
+	Hs
		234890 FYN_HUMAN (18-510): 0: 543: 38.64		SNX3_HUMAN (5-162): 2.59e-55: 173: 79.75
+	Hs
		523230 SRC_HUMAN (13-510): 0: 547: 38.58		SNX9_HUMAN (23-161): 1.52e-32: 123: 19.86
+	Hs
		433518 YES_HUMAN (5-510): 3.73e-179: 537: 39.42		SNX9_HUMAN (23-161): 1.52e-32: 123: 19.86
+	Hs
		434102 LYN_HUMAN (9-508): 9.12e-173: 519: 36.15		SNX9_HUMAN (23-161): 1.52e-32: 123: 19.86
+	Ce
		106681 SRC1_CAEEL (9-508): 5.12e-160: 487: 36.52		LST4_CAEEL (2-161): 7.02e-31: 118: 22.09
+	Hs
		789017 TEC_HUMAN (40-502): 5.28e-154: 475: 36.71		SNX9_HUMAN (23-161): 1.52e-32: 123: 19.86