HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17474147
Identification Methods peptide array
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_1, PK_Tyr_Ser-Thr~SH3_9, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0001726 - ruffle
GO:0005737 - cytoplasm
GO:0006979 - response to oxidative stress
GO:0015629 - actin cytoskeleton
GO:0017124 - SH3 domain binding
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1130
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024