HitPredict

Interactor 1: ABL (P00522)
Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)
Gene: ABL

Interactor 2: LAR (P16621)
Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR)
Gene: LAR

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 10069336, 21931847
Identification Methods affinity chromatography technology, enzymatic study, pull down, protein kinase assay, phosphatase assay
Interaction Type physical association, direct interaction, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase, SH2~fn3, SH2~Y_phosphatase
Common GO terms GO:0007411 - axon guidance
GO:0008045 - motor neuron axon guidance
GO:0030424 - axon
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1620
Dm

1 2029
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Last updated: 15 Jul 2024