HitPredict

Interactor 1: ABL (P00522)
Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)
Gene: ABL

Interactor 2: PTP99 (P35832)
Tyrosine-protein phosphatase 99A (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 99A) (DPTP99A)
Gene: Ptp99A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	21931847
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase, SH2~fn3, SH2~Y_phosphatase
Common GO terms	GO:0008045 - motor neuron axon guidance GO:0030424 - axon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1620 Dm			1 1301
+	Dm
		337643 ABL_DROME (1-1620): 0: 1588: 100.00		PTP69_DROME (11-347): 1.58e-25: 117: 15.06
+	Dm
		337644 ABL_DROME (1-1620): 0: 1588: 100.00		LAR_DROME (2-563): 8.24e-24: 111: 10.14
+	Hs
		412018 FYN_HUMAN (117-639): 0: 563: 38.53		PTPRZ_HUMAN (758-1150): 1.23e-112: 393: 15.88
+	Rn
		1146020 SRC_RAT (108-639): 0: 588: 37.48		Q66HJ7_RAT (747-1145): 7.11e-106: 355: 18.78
+	Hs
		433255 YES_HUMAN (105-639): 0: 569: 38.07		PTPRE_HUMAN (716-1165): 6.49e-113: 372: 18.86
+	Hs
		522756 SRC_HUMAN (102-639): 0: 581: 37.25		PTPRA_HUMAN (747-1145): 1.94e-106: 357: 18.78
+	Rn
		976063 SRC_RAT (108-639): 0: 588: 37.48		PTPRA_RAT (747-1145): 1.74e-103: 349: 18.33
+	Hs
		412017 FYN_HUMAN (117-639): 0: 563: 38.53		PTPRE_HUMAN (716-1165): 6.49e-113: 372: 18.86
+	Mm
		403413 SRC_MOUSE (108-639): 0: 587: 37.48		PTPRA_MOUSE (747-1145): 2.64e-99: 338: 17.36
+	Hs
		411997 FYN_HUMAN (117-639): 0: 563: 38.53		PTPRA_HUMAN (747-1145): 1.94e-106: 357: 18.78
+	Rn
		1144045 FYN_RAT (118-639): 0: 562: 38.61		Q66HJ7_RAT (747-1145): 7.11e-106: 355: 18.78
+	Hs
		523222 SRC_HUMAN (102-639): 0: 581: 37.25		PTN22_HUMAN (460-797): 2.91e-93: 321: 29.77
+	Mm
		574000 FYN_MOUSE (118-639): 0: 563: 38.80		PTPRA_MOUSE (747-1145): 2.64e-99: 338: 17.36
+	Rn
		94284 FYN_RAT (118-639): 0: 562: 38.61		F1LXJ9_RAT (20-391): 8.84e-35: 147: 14.29
+	Mm
		337619 ABL1_MOUSE (151-1200): 0: 624: 40.59		PTN11_MOUSE (786-967): 4.67e-14: 79: 29.00
+	Hs
		411959 FYN_HUMAN (117-639): 0: 563: 38.53		PTPRF_HUMAN (2-493): 4e-24: 112: 11.04
+	Mm
		56907 FYN_MOUSE (118-639): 0: 563: 38.80		PTPRF_MOUSE (2-562): 7.86e-24: 111: 11.46
+	Hs
		412016 FYN_HUMAN (117-639): 0: 563: 38.53		PTPRD_HUMAN (2-562): 3.52e-23: 109: 11.88
+	Hs
		441169 SRC_HUMAN (102-639): 0: 581: 37.25		PTPRC_HUMAN (33-258): 1.17e-12: 74.9: 14.72
+	Hs
		411950 FYN_HUMAN (117-639): 0: 563: 38.53		PTPRC_HUMAN (33-258): 1.17e-12: 74.9: 14.72