HitPredict

Interactor 1: SRC64 (P00528)
Tyrosine-protein kinase Src64B (Dsrc64) (EC 2.7.10.2)
Gene: Src64B

Interactor 2: Q8INY1 (Q8INY1)
Suppressor of cytokine signaling at 36E, isoform D
Gene: Socs36E

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2, SH2~SH2, SH2~SOCS_box, SH2~SH3_1
Common GO terms	GO:0007616 - long-term memory
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 552 Dm			1 737
+	Dm
		337701 SRC64_DROME (1-552): 0: 592: 100.00		Q9VJA1_DROME (1-633): 0: 657: 100.00
+	Hs
		433231 YES_HUMAN (5-549): 0: 565: 45.42		SRC_HUMAN (307-646): 2.77e-46: 175: 14.55
+	Hs
		146582 YES_HUMAN (5-549): 0: 565: 45.42		SOCS2_HUMAN (431-613): 6.69e-49: 172: 28.28
+	Dm
		186276 SRC64_DROME (1-552): 0: 592: 100.00		O18683_DROME (431-576): 9.88e-35: 140: 22.82
+	Hs
		411946 YES_HUMAN (5-549): 0: 565: 45.42		FYN_HUMAN (351-601): 1.01e-43: 167: 15.59
+	Hs
		146668 YES_HUMAN (5-549): 0: 565: 45.42		SOCS7_HUMAN (285-612): 2.11e-42: 164: 21.17
+	Hs
		411552 YES_HUMAN (5-549): 0: 565: 45.42		LCK_HUMAN (384-628): 1.8e-42: 163: 13.89
+	Mm
		763403 FYN_MOUSE (31-549): 0: 551: 45.98		NCK1_MOUSE (305-557): 1.12e-48: 177: 17.76
+	Hs
		147377 YES_HUMAN (5-549): 0: 565: 45.42		SOCS3_HUMAN (435-610): 7.01e-45: 162: 24.20
+	Hs
		411969 FYN_HUMAN (31-549): 0: 550: 45.79		SRC_HUMAN (307-646): 2.77e-46: 175: 14.55
+	Hs
		433263 YES_HUMAN (5-549): 0: 565: 45.42		P85A_HUMAN (468-640): 4.84e-40: 159: 21.47
+	Hs
		411936 FYN_HUMAN (31-549): 0: 550: 45.79		FYN_HUMAN (351-601): 1.01e-43: 167: 15.59
+	Hs
		181770 YES_HUMAN (5-549): 0: 565: 45.42		SOCS1_HUMAN (450-613): 9.39e-41: 150: 25.61
+	Hs
		411545 FYN_HUMAN (31-549): 0: 550: 45.79		LCK_HUMAN (384-628): 1.8e-42: 163: 13.89
+	Mm
		643066 FYN_MOUSE (31-549): 0: 551: 45.98		P85A_MOUSE (469-640): 4.18e-40: 159: 21.59
+	Hs
		181765 FYN_HUMAN (31-549): 0: 550: 45.79		SOCS1_HUMAN (450-613): 9.39e-41: 150: 25.61
+	Dm
		337676 SRC64_DROME (1-552): 0: 592: 100.00		GRAP_DROME (461-596): 2.65e-15: 77.2: 21.17
+	Hs
		433433 YES_HUMAN (5-549): 0: 565: 45.42		P55G_HUMAN (470-582): 6.9e-19: 92.2: 21.55
+	Mm
		763400 FYN_MOUSE (31-549): 0: 551: 45.98		PLCG2_MOUSE (463-633): 1.51e-22: 105: 17.50
+	Hs
		129164 FYN_HUMAN (31-549): 0: 550: 45.79		P85B_HUMAN (464-570): 5.41e-22: 103: 24.55